ARI Publication 40 – 2013 Version ARI Survey of Parent Ratings of Treatment Efficacy: % Worse % No Change % Better Number of Reports Digestive Enzymes 3% 35% 62% 2350 Specific Carbohydrate Diet 7% 22% 71% 537 29 PREVIOUS NEXT Agape is proud to have been involved in this study and mentioned on…
ARI Publication 40 – 2013 Version For more info, see the review by Rossignol and Frye, Melatonin in autism spectrum disorders: a systematic review and meta-analysis. Dev Med Child Neural 2011 Sep;53(9):783-92 37 PREVIOUS NEXT Agape is proud to have been involved in this study and mentioned on page 16.> ORDER NOW Share This…
ARI Publication 40 – 2013 Version Melatonin Rationale: Many children and adults with autism have sleep problems, including falling asleep,nighttime waking, and early waking. These sleep problems have a strong correlation with gutproblems, and healing the gut seems to reduce many of those sleep problems.However, if sleep problems continue, supplementation with melatonin can help.…
AR Publication 40 – 2013 Version PARENT RATINGS OF BEHAVIORAL EFFECTS OF BIOMEDICAL INTERVENTIONS Autism Research Institute • 4182 Adams Avenue • San Diego, CA 92116The parents of autistic children represent a vast and important reservoir of information on the benefits-and adverse effect-softhe large variety of drugs and other interventions that have been tried with…
ARI Publication 40 – 2013 Version Summary Autism is a very complex disorder, and involves many genetic and environmental factorsthat are not well-understood. However, there are many biomedical abnormalities that havebeen identified, and most can be treated to some degree. By following the testing andtreatments outlined above, many individuals will improve to some degree,…
ARI Publication 40 – 2013 Version Ito H etal, Rndingsofbrain 99mTc-EGJSPECTin high-li.Jnctioningautism-3-dimensionalstereotadicROItemplateanalysisofbrain SPECT. J MedInvest. 2005Feb;52(1-2):49-56. (15d7i/clren with autism, 5 d7ilclren withepilepsy)Gupta SK, Ratnam BV. Cerebralperfusion abnormalities in children with autism and mental retardation:a segmental quantitative SPECTstudy. Indian Pediatr. 2009 Feb;46(2):161-4. (10 children withautism, 5 typical children)Sasaki M, et al Brain perfusion SPECT and…
ARI Publication 40 – 2013 Version CGI, ABC, and ATEC scales, but the differences between treatment and placebo groups were notstatistically significant. Rossignol DA, et al: Hyperbaric treatment for children with autism: a multicenter, randomized, doubleblind, controlled trial BMCPediatr 2009, 9:21. Another randomized, double-blind, placebo-controlled study involved 46 children with autismundergoing 80 sessions (1.3…
ARI Publication 40 – 2013 Version Research on Treatment: There are several open-label studies of HBOT therapy for children, and most suggest that HBOTtherapy might be helpful, but one open-label study with rigorous pre/post assessment showed nobenefit. There are also two randomized, double-blind, placebo-controlled studies, with one studyshowing statistically significant benefit in one of…
ARI Publication 40 – 2013 Version Hyperbaric Oxygen Therapy (HBOT) Rationale: There is substantial evidence of decreased blood flow in brains of most children withautism, suggesting a need for more oxygen. HBOT is an effective method to temporarily increaseoxygen levels throughout the body. It is effective for improving general wound healing, and mighthelp with…
ARI Publication 40 – 2013 Version ACTOS: ACTOS (pioglitazone) has multiple effects, including the ability to decrease inflammation.An open study of ACTOS in 25 children with autism for 3-4 months found substantial improvements in irritability, lethargy, stereotypy, and hyperactivity, with greater benefits in the younger children.Doses were 30 mg (younger children) and 60 mg (older…
