Summaries

Summary of Dietary, Nutritional, and Medical Treatments for Autism – 36

  ARI Publication 40 – 2013 Version Melatonin Rationale: Many children and adults with autism have sleep problems, including falling asleep,nighttime waking, and early waking. These sleep problems have a strong correlation with gutproblems, and healing the gut seems to reduce many of those sleep problems.However, if sleep problems continue, supplementation with melatonin can help. …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 53

AR Publication 40 – 2013 Version PARENT RATINGS OF BEHAVIORAL EFFECTS OF BIOMEDICAL INTERVENTIONS Autism Research Institute • 4182 Adams Avenue • San Diego, CA 92116The parents of autistic children represent a vast and important reservoir of information on the benefits-and adverse effect-softhe large variety of drugs and other interventions that have been tried with …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 52

  ARI Publication 40 – 2013 Version Summary Autism is a very complex disorder, and  involves many genetic and environmental factorsthat are not well-understood. However, there are many biomedical abnormalities that havebeen identified, and most can be treated to some degree. By following the testing andtreatments outlined above, many individuals will improve to some degree, …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 51

  ARI Publication 40 – 2013 Version Ito H etal, Rndingsofbrain 99mTc-EGJSPECTin high-li.Jnctioningautism-3-dimensionalstereotadicROItemplateanalysisofbrain SPECT. J MedInvest. 2005Feb;52(1-2):49-56. (15d7i/clren with autism, 5 d7ilclren withepilepsy)Gupta SK, Ratnam BV. Cerebralperfusion abnormalities in children with autism and mental retardation:a segmental quantitative SPECTstudy. Indian Pediatr. 2009 Feb;46(2):161-4. (10 children withautism, 5 typical children)Sasaki M, et al Brain perfusion SPECT and …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 50

  ARI Publication 40 – 2013 Version CGI, ABC, and ATEC scales, but the differences between treatment and placebo groups were notstatistically significant. Rossignol DA, et al: Hyperbaric treatment for children with autism: a multicenter, randomized, doubleblind, controlled trial BMCPediatr 2009, 9:21. Another randomized, double-blind, placebo-controlled study involved 46 children with autismundergoing 80 sessions (1.3 …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 49

  ARI Publication 40 – 2013 Version Research on Treatment: There are several open-label studies of HBOT therapy for children, and most suggest that HBOTtherapy might be helpful, but one open-label study with rigorous pre/post assessment showed nobenefit. There are also two randomized, double-blind, placebo-controlled studies, with one studyshowing statistically significant benefit in one of …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 48

  ARI Publication 40 – 2013 Version Hyperbaric Oxygen Therapy (HBOT) Rationale: There is substantial evidence of decreased blood flow in brains of most children withautism, suggesting a need for more oxygen. HBOT is an effective method to temporarily increaseoxygen levels throughout the body. It is effective for improving general wound healing, and mighthelp with …

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Summary of Dietary, Nutritional, and Medical Treatments for Autism – 47

ARI Publication 40 – 2013 Version ACTOS: ACTOS (pioglitazone) has multiple effects, including the ability to decrease inflammation.An open study of ACTOS in 25 children with autism for 3-4 months found substantial improvements in irritability, lethargy, stereotypy, and hyperactivity, with greater benefits in the younger children.Doses were 30 mg (younger children) and 60 mg (older …

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